A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.

N, Bouatia-Naji; G, Rocheleau; Lommel L, Van; K, Lemaire; F, Schuit; C, Cavalcanti-Proença; M, Marchand; AL, Hartikainen; U, Sovio; Graeve F, De; J, Rung; M, Vaxillaire; J, Tichet; M, Marre; B, Balkau; J, Weill; P, Elliott; MR, Jarvelin; D, Meyre; C, Polychronakos; C, Dina; R, Sladek; P, Froguel

doi:10.1126/science.1156849

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A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.

Shared by NobleBlocks on May 1, 2008 • 12:00 AM UTC

Authors:

Bouatia-Naji N

Rocheleau G

Van Lommel L

Abstract

Several studies have shown that healthy individuals with fasting plasma glucose (FPG) levels at the high end of the normal range have an increased risk of mortality. To identify genetic determinants that contribute to interindividual variation in FPG, we tested 392,935 single-nucleotide polymorphism...

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