A twofold increase in BRCA mutation related prostate cancer among Ashkenazi Israelis is not associated with distinctive histopathology

M. Giusti, Ruthann; L Rutter, J; H Duray, P; S Freedman, L; Konichezky, M; Fisher-Fischbein, J; H Greene, M; Maslansky, B; Fischbein, A; B Gruber, S; Rennert, G; D Ronchetti, R; M Hewitt, S; P Struewing, J; Iscovich, J

doi:10.1136/jmg.40.10.787

Public

A twofold increase in BRCA mutation related prostate cancer among Ashkenazi Israelis is not associated with distinctive histopathology

Published in Journal of Medical Genetics • Oct 1, 2003

Authors:

Ruthann M. Giusti

J L Rutter

P H Duray

Abstract

T he magnitude of the risk of prostate cancer among Ashkenazi Jewish carriers of the common mutations in the BRCA1 and BRCA2 genes, the so-called Ashkenazi BRCA founder mutations (BRCA1 185delAG and 5382insC, and BRCA2 6174delT), remains uncertain. Two large epidemiological studies have suggested th...

Subject

Prostate cancer

Medicine

Cancer

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