NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both
                    <i>In Vitro</i>
                    and
                    <i>In Vivo</i>

Liu, Yitao; Pan Wong, Tak; Aarts, Michelle; Rooyakkers, Amanda; Liu, Lidong; Weita Lai, Ted; Chuan Wu, Dong; Lu, Jie; Tymianski, Michael; Marie Craig, Ann; Tian Wang, Yu

doi:10.1523/jneurosci.0116-07.2007

Public

NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In Vivo

Shared by NobleBlocks on Mar 14, 2007 • 12:00 AM UTC

Authors:

Yitao Liu

Tak Pan Wong

Michelle Aarts

Abstract

Well-documented experimental evidence from both in vitro and in vivo models of stroke strongly supports the critical involvement of NMDA receptor-mediated excitotoxicity in neuronal damage after stroke. Despite this, the results of clinical trials testing NMDA receptor antagonists as neuroprotectant...

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