Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing

Liu, Pengyuan; Morrison, Carl; Wang, Liang; Xiong, Donghai; T. Vedell, Peter; Cui, Peng; Hua, Xing; Ding, Feng; Lü, Yan; A. James, Michael; D. Ebben, John; Xu, Haiming; A. Adjei, Alex; Head, Karen; Wendt Andrae, Jaime; Tschannen, Michael; J. Jacob, Howard; Pan, Jing; Zhang, Qi; Van den Bergh, Françoise; Xiao, Haijie; C. Lo, Ken; Patel, Jigar; Richmond, Todd; Watt, Mary-Anne; Albert, Thomas; R. Selzer, Rebecca; W. Anderson, Marshall; Wang, Jiang; Wang, Yian; L. Starnes, Sandra; Yang, Ping; You, Ming

doi:10.1093/carcin/bgs148

Public

Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing

Published in Carcinogenesis • Apr 17, 2012

Authors:

Pengyuan Liu

Carl Morrison

Liang Wang

Abstract

Lung cancer is the leading cause of cancer-related death, with non-small cell lung cancer (NSCLC) being the predominant form of the disease. Most lung cancer is caused by the accumulation of genomic alterations due to tobacco exposure. To uncover its mutational landscape, we performed whole-exome se...

Subject

Lung cancer

Exome sequencing

CDKN2A

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