Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing.

P, Liu; C, Morrison; L, Wang; D, Xiong; P, Vedell; P, Cui; X, Hua; F, Ding; Y, Lu; M, James; JD, Ebben; H, Xu; AA, Adjei; K, Head; JW, Andrae; MR, Tschannen; H, Jacob; J, Pan; Q, Zhang; den Bergh F, Van; H, Xiao; KC, Lo; J, Patel; T, Richmond; MA, Watt; T, Albert; R, Selzer; M, Anderson; J, Wang; Y, Wang; S, Starnes; P, Yang; M, You

doi:10.1093/carcin/bgs148

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Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing.

Shared by NobleBlocks on Apr 17, 2012 • 12:00 AM UTC

Authors:

Liu P

Morrison C

Wang L

Abstract

Lung cancer is the leading cause of cancer-related death, with non-small cell lung cancer (NSCLC) being the predominant form of the disease. Most lung cancer is caused by the accumulation of genomic alterations due to tobacco exposure. To uncover its mutational landscape, we performed whole-exome se...

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