Clinical and Molecular Characterization of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

G. Priori, Silvia; Napolitano, Carlo; Memmi, Mirella; Colombi, Barbara; Drago, Fabrizio; Gasparini, Maurizio; DeSimone, Luciano; Coltorti, Fernando; Bloise, Raffaella; Keegan, Roberto; E.S. Cruz Filho, Fernando; Vignati, Gabriele; Benatar, Abraham; DeLogu, Angelica

doi:10.1161/01.cir.0000020013.73106.d8

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Clinical and Molecular Characterization of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

Shared by NobleBlocks on Jul 2, 2002 • 12:00 AM UTC

Authors:

Silvia G. Priori

Carlo Napolitano

Mirella Memmi

Abstract

Background — Mutations in the cardiac ryanodine receptor gene ( RyR2 ) underlie catecholaminergic polymorphic ventricular tachycardia (CPVT), an inherited arrhythmogenic disease occurring in the structurally intact heart. The proportion of patients with CPVT carrying RyR2 mutations is unknown, and t...

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