Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

I. Smith, Michelle; Yatsunenko, Tanya; Manary, Mark; Trehan, Indi; Sawasawa Mkakosya, Rajhab; Cheng, Jiye; L. Kau, Andrew; S. Rich, Stephen; Concannon, Patrick; C. Mychaleckyj, Josyf; Liu, Jie; R. Houpt, Eric; V. Li, Jia; Holmes, Elaine; K. Nicholson, Jeremy; Knights, Dan; K. Ursell, Luke; Knight, Rob; I. Gordon, Jeffrey

doi:10.1126/science.1229000

Public

Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor

Published in Science • Jan 30, 2013

Authors:

Michelle I. Smith

Tanya Yatsunenko

Mark Manary

Abstract

Kwashiorkor, an enigmatic form of severe acute malnutrition, is the consequence of inadequate nutrient intake plus additional environmental insults. To investigate the role of the gut microbiome, we studied 317 Malawian twin pairs during the first 3 years of life. During this time, half of the twin ...

Subject

Kwashiorkor

Severe Acute Malnutrition

Malnutrition

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