Mutation in <i>TET2</i> in Myeloid Cancers

Delhommeau, François; Dupont, Sabrina; Della Valle, Véronique; James, Chloé; Trannoy, Séverine; Massé, Aline; Kosmider, Olivier; Le Couedic, Jean‐Pierre; Miller Robert, F.; Alberdi, A.; Lécluse, Yann; Plo, Isabelle; Dreyfus, François; Marzac, Christophe; Casadevall, Nicole; Lacombe, Catherine; Romana, Serge; Dessen, Philippe; Soulier, Jean; Viguié, F; Fontenay, Michaëla; Vainchenker, William; Bernard, Olivier

doi:10.1056/nejmoa0810069

Public

Mutation in TET2 in Myeloid Cancers

Published in New England Journal of Medicine • May 27, 2009

Authors:

François Delhommeau

Sabrina Dupont

Véronique Della Valle

Abstract

BACKGROUND: The myelodysplastic syndromes and myeloproliferative disorders are associated with deregulated production of myeloid cells. The mechanisms underlying these disorders are not well defined. METHODS: We conducted a combination of molecular, cytogenetic, comparative-genomic-hybridization, an...

Subject

Myelodysplastic syndromes

Myeloproliferative Disorders

Myeloid

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