Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: The Randomized Double-Blind Reminder Study

Montalescot, Gilles; Pitt, Bertram; López de Sá, Esteban; W. Hamm, Christian; Flather, Marcus; W.A. Verheugt, Freek; Shi, Harry; Turgonyi, Eva; Orri, Miguel; Vincent, John; Zannad, Faı̈ez; the REMINDER Investigators, for; Noll, G.; A.P. Weir, Robin; J. O’Neill, Blair; Böhm, Michael; Hillis, WS; Grieve, Andrew; L Rouleau, J; Gerasimos, Filippatos; Fitchett, David; Lepage, Serge; Madan, Mina; Sussex, Bruce; Tremblay, Guy; C. Welsh, Robert; Wong, G; Hutyra, Martin; Kettner, Jiří; Ostadal, P.; Špinar, Jindřich; Vojáček, Jan; Barboteu, M.; Collet, J.‐P.; Coste, Pierre; Cottin, Yves; Ducos, D.; Galinier, Michel; Teíger, Emmanuel; Zemour, Gilles; Bauersachs, Johann; Hambrecht, Rainer; F. Hauf, Gerhard; Heuer, H; Mudra, Harald; Münzel, Thomas; Steiner, Stephan; H. Strasser, R.; Sydow, K.; Tschöpe, Carsten; Wachter, Rolf; Werner, Nicolas; Alexopoulos, D.; Babalis, D.; Pyrgakis, Vlasios; András Dézsi, Csaba; Lupkovics, Géza; Polgàr, Péter; Tomcsányi, János; Herrman, Jean-Paul; M. ten Berg, J.; Górny, Jerzy; Kubica, Jacek; Lewczuk, Jerzy; Żmuda, Witold; Hranai, Marián; Kovar, F.; Margoczy, Roman; Micko, Karol; Sumbal, J; B. Genover, X.; F. Ortiz, A.; F. Sala, M.; G. Garcia, C.; P. Munoz, C.; Ramón Rey Blas, Juan; Ridocci Soriano, Francisco; Adamson, D.L.; Alamgir, Farqad; Chauhan, Ashok; Y.H. Lip, Gregory; Martin, Trejeeve; P McCann, Gerry; E. Newby, David; W. Smith, David

doi:10.1093/eurheartj/ehu164

Public

Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: The Randomized Double-Blind Reminder Study

Published in European Heart Journal • Apr 29, 2014

Authors:

Gilles Montalescot

Bertram Pitt

Esteban López de Sá

Abstract

AIMS: We aimed to assess the impact of eplerenone on cardiovascular (CV) outcomes in STEMI without known heart failure, when initiated within 24 h of symptom onset. METHODS AND RESULTS: In this randomized, placebo-controlled, double-blind trial, we assigned 1012 patients with acute STEMI and without...

Subject

Medicine

Eplerenone

Internal medicine

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