Impact of HIV-1 Subtype and Antiretroviral Therapy on Protease and Reverse Transcriptase Genotype: Results of a Global Collaboration

Kantor, Rami; Katzenstein, David; Efron, Brad; Carvalho, A.P.; Wynhoven, Brian; Cane, Patricia; Clarke, John; Sirivichayakul, Sunee; A. Soares, Marcelo; Snoeck, Joke; Pillay, Candice; Rudich, H; Rodrigues, Rosângela; Holguín, África; Ariyoshi, Koya; Belén Bouzas, María; Cahn, Pedro; Sugiura, Wataru; Soriano, Vincent; Fernando de Macedo Brígido, Luís; Grossman, Zehava; Morris, Lynn; Vandamme, Anne‐Mieke; Tanuri, Amílcar; Phanuphak, Praphan; Weber, Jonathan; Pillay, Deenan; Richard Harrigan, P.; Camacho, Ricardo; Schapiro, Jonathan; W. Shafer, Robert

doi:10.1371/journal.pmed.0020112

Public

Impact of HIV-1 Subtype and Antiretroviral Therapy on Protease and Reverse Transcriptase Genotype: Results of a Global Collaboration

Published in PLoS Medicine • Apr 19, 2005

Authors:

Rami Kantor

David Katzenstein

Brad Efron

Abstract

BACKGROUND: The genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral treatment is expanded to regions of the world where diverse non-subtype-B viruses predominate. METHODS AND FINDINGS: To assess the impact of HIV-1 subtyp...

Subject

Reverse transcriptase

Virology

Drug resistance

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