Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)

Dougados, Maxime; Kissel, K.; Sheeran, Tom; P. Tak, Paul; G. Conaghan, Philip; Martín Mola, Emilio; Schett, Georg; Amital, Howard; Navarro-Sarabia, F.; Hou, Antony; Bernasconi, Corrado; Huizinga, T.

doi:10.1136/annrheumdis-2011-201282

Public

Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)

Published in Annals of the Rheumatic Diseases • Jul 8, 2012

Authors:

Maxime Dougados

K. Kissel

Tom Sheeran

Abstract

OBJECTIVE: In patients with active rheumatoid arthritis (RA) despite methotrexate, to compare the efficacy of adding tocilizumab to that of switching to tocilizumab monotherapy. METHODS: Double-blind, 2-year study in which adults with active RA (DAS28 >4.4) despite methotrexate were randomly assigne...

Subject

Tocilizumab

Medicine

Rheumatoid arthritis

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