A Randomized Trial of Aspirin to Prevent Colorectal Adenomas

A. Baron, John; F. Cole, Bernard; S. Sandler, Robert; W. Haile, Robert; J. Ahnen, Dennis; S. Bresalier, Robert; McKeown‐Eyssen, Gail; W. Summers, Robert; Rothstein, Richard; A. Burke, Carol; C. Snover, Dale; R. Church, Timothy; I. Allen, John; Beach, Michael; J. Beck, Gerald; H. Bond, John; Byers, Tim; Robert Greenberg, E.; S. Mandel, Jack; E. Marcon, Norman; A. Mott, Leila; Pearson, Loretta; Saibil, Fred; U. van Stolk, Rosalind

doi:10.1056/nejmoa021735

Public

A Randomized Trial of Aspirin to Prevent Colorectal Adenomas

Published in New England Journal of Medicine • Mar 5, 2003

Authors:

John A. Baron

Bernard F. Cole

Robert S. Sandler

Abstract

BACKGROUND: Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel. METHODS: We performed a randomized, double-blind trial of aspirin as a chemopreventive agent against colorectal adenomas. We randomly assigned 1121 patients with a recent history of hi...

Subject

Medicine

Aspirin

Colonoscopy

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