Trial of Early, Goal-Directed Resuscitation for Septic Shock

Mouncey, Paul; M. Osborn, Tiffany; Sarah Power, G.; A Harrison, David; Sadique, Zia; Grieve, Richard; Jahan, Rahi; Harvey, Sheila; Bell, Derek; Bion, Julian; Coats, Tim; Singer, Mervyn; Young, Duncan; Rowan, Kathy

doi:10.1056/nejmoa1500896

Public

Trial of Early, Goal-Directed Resuscitation for Septic Shock

Published in New England Journal of Medicine • Mar 17, 2015

Authors:

Paul Mouncey

Tiffany M. Osborn

G. Sarah Power

Abstract

BACKGROUND: Early, goal-directed therapy (EGDT) is recommended in international guidelines for the resuscitation of patients presenting with early septic shock. However, adoption has been limited, and uncertainty about its effectiveness remains. METHODS: We conducted a pragmatic randomized trial wit...

Subject

Medicine

Early goal-directed therapy

Resuscitation

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