Characterization and Manipulation of the Pathway-Specific Late Regulator AlpW Reveals<i>Streptomyces ambofaciens</i>as a New Producer of Kinamycins

Bunet, Robert; Song, Lijiang; V. Mendes, Marta; Corre, Christophe; Hôtel, Laurence; Rouhier, Nicolas; Framboisier, Xavier; Leblond, Pierre; L. Challis, Gregory; Aigle, Bertrand

doi:10.1128/jb.01269-10

Public

Characterization and Manipulation of the Pathway-Specific Late Regulator AlpW RevealsStreptomyces ambofaciensas a New Producer of Kinamycins

Published in Journal of Bacteriology • Dec 31, 2010

Authors:

Robert Bunet

Lijiang Song

Marta V. Mendes

Abstract

The genome sequence of Streptomyces ambofaciens, a species known to produce the congocidine and spiramycin antibiotics, has revealed the presence of numerous gene clusters predicted to be involved in the biosynthesis of secondary metabolites. Among them, the type II polyketide synthase-encoding alp ...

Subject

Regulator

Characterization (materials science)

Streptomyces

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