Pituitary macroadenoma in a 5-year-old: an early expression of multiple endocrine neoplasia type 1.

CA, Stratakis; DH, Schussheim; SM, Freedman; MF, Keil; SD, Pack; SK, Agarwal; MC, Skarulis; RJ, Weil; IA, Lubensky; Z, Zhuang; EH, Oldfield; SJ, Marx

doi:10.1210/jcem.85.12.7064

Public

Pituitary macroadenoma in a 5-year-old: an early expression of multiple endocrine neoplasia type 1.

Shared by NobleBlocks on Dec 1, 2000 • 12:00 AM UTC

Authors:

Stratakis CA

Schussheim DH

Freedman SM

Abstract

Multiple endocrine neoplasia type 1 (MEN 1) is associated with parathyroid, enteropancreatic, pituitary, and other tumors. The MEN1 gene, a tumor suppressor, is located on chromosome 11. Affected individuals inherit a mutated MEN1 allele, and tumorigenesis in specific tissues follows inactivation of...

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