Association of Hydroxyethyl Starch Administration With Mortality and Acute Kidney Injury in Critically Ill Patients Requiring Volume Resuscitation

Zarychanski, Ryan; M Abou-Setta, Ahmed; F. Turgeon, Alexis; L. Houston, Brett; McIntyre, Lauralyn; C. Marshall, John; Fergusson, Dean

doi:10.1001/jama.2013.430

Public

Association of Hydroxyethyl Starch Administration With Mortality and Acute Kidney Injury in Critically Ill Patients Requiring Volume Resuscitation

Published in JAMA • Feb 19, 2013

Authors:

Ryan Zarychanski

Ahmed M Abou-Setta

Alexis F. Turgeon

Abstract

IMPORTANCE: Hydroxyethyl starch is commonly used for volume resuscitation yet has been associated with serious adverse events, including acute kidney injury and death. Clinical trials of hydroxyethyl starch are conflicting. Moreover, multiple trials from one investigator have been retracted because ...

Subject

Hydroxyethyl starch

Medicine

Acute kidney injury

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