<i>Mycobacterium tuberculosis</i>
                    Growth at theCavity Surface: a Microenvironment with FailedImmunity

Kaplan, Gilla; A. Post, Frank; L. Moreira, Andre; Wainwright, Helen; N. Kreiswirth, Barry; Tanverdi, Melike; Mathema, Barun; V. Ramaswamy, Srinivas; Walther, Gabi; M. Steyn, Lafras; E. Barry, Clifton; Bekker, Linda-Gail

doi:10.1128/iai.71.12.7099-7108.2003

Public

Mycobacterium tuberculosis Growth at theCavity Surface: a Microenvironment with FailedImmunity

Shared by NobleBlocks on Dec 1, 2003 • 12:00 AM UTC

Authors:

Gilla Kaplan

Frank A. Post

Andre L. Moreira

Abstract

ABSTRACT Protective immunity against pulmonary tuberculosis (TB) is characterized by the formation in the lungs of granulomas consisting of macrophages and activated T cells producing tumor necrosis factor alpha and gamma interferon, both required for the activation of the phagocytes. In 90% of immu...

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