Five-Year Outcomes of a Randomized Phase III Trial Comparing Adjuvant Chemotherapy With S-1 Versus Surgery Alone in Stage II or III Gastric Cancer

Sasako, Mitsuru; Sakuramoto, Shinichi; Katai, Hitoshi; Kinoshitá, Taira; Furukawa, Hiroshi; Yamaguchi, Toshiharu; Nashimoto, Atsushi; Fujii, Masashi; Nakajima, Toshifusa; Ohashi, Yasuo

doi:10.1200/jco.2011.36.5908

Public

Five-Year Outcomes of a Randomized Phase III Trial Comparing Adjuvant Chemotherapy With S-1 Versus Surgery Alone in Stage II or III Gastric Cancer

Published in Journal of Clinical Oncology • Oct 18, 2011

Authors:

Mitsuru Sasako

Shinichi Sakuramoto

Hitoshi Katai

Abstract

PURPOSE: The first planned interim analysis (median follow-up, 3 years) of the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer confirmed that the oral fluoropyrimidine derivative S-1 significantly improved overall survival, the primary end point. The results were therefore opened at the recomm...

Subject

Medicine

Hazard ratio

Interim analysis

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