Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

Widmann, Christian; B. Gibson, Spencer; Jarpe, Matthew; L. Johnson, Gary

doi:10.1152/physrev.1999.79.1.143

Public

Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human

Published in Physiological Reviews • Jan 1, 1999

Authors:

Christian Widmann

Spencer B. Gibson

Matthew Jarpe

Abstract

Mitogen-activated protein kinases (MAPK) are serine-threonine protein kinases that are activated by diverse stimuli ranging from cytokines, growth factors, neurotransmitters, hormones, cellular stress, and cell adherence. Mitogen-activated protein kinases are expressed in all eukaryotic cells. The b...

Subject

MAPK/ERK pathway

Cell biology

Protein kinase A

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