Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma

O. Nielsen, Torsten; D. Hsu, Forrest; C. Jensen, Kristin; C.U. Cheang, Maggie; Karaca, Gamze; Hu, Zhiyuan; Hernandez‐Boussard, Tina; Livasy, Chad; Cowan, Dave; G. Dressler, Lynn; A. Akslen, Lars; Ragaz, Joseph; M. Gown, Allen; Blake Gilks, C.; van de Rijn, Matt; M. Perou, Charles

doi:10.1158/1078-0432.ccr-04-0220

Public

Immunohistochemical and Clinical Characterization of the Basal-Like Subtype of Invasive Breast Carcinoma

Published in Clinical Cancer Research • Aug 15, 2004

Authors:

Torsten O. Nielsen

Forrest D. Hsu

Kristin C. Jensen

Abstract

PURPOSE: Expression profiling studies classified breast carcinomas into estrogen receptor (ER)+/luminal, normal breast-like, HER2 overexpressing, and basal-like groups, with the latter two associated with poor outcomes. Currently, there exist clinical assays that identify ER+/luminal and HER2-overex...

Subject

Cytokeratin

Tissue microarray

Immunohistochemistry

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