A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice.

Fernando F, Anhê,; Denis, Roy,; Geneviève, Pilon,; Stéphanie, Dudonné,; Sébastien, Matamoros,; Thibault V, Varin,; Carole, Garofalo,; Quentin, Moine,; Yves, Desjardins,; Emile, Levy,; André, Marette,

doi:10.1136/gutjnl-2014-307142

Public

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice.

Published in Gut • Jun 1, 2015

Authors:

Anhê, Fernando F

Roy, Denis

Pilon, Geneviève

Abstract

OBJECTIVE: The increasing prevalence of obesity and type 2 diabetes (T2D) demonstrates the failure of conventional treatments to curb these diseases. The gut microbiota has been put forward as a key player in the pathophysiology of diet-induced T2D. Importantly, cranberry (Vaccinium macrocarpon Aito...

Subject

Diabetes Mellitus

Intestinal Bacteria

Intestinal Permeability

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