Impact of Adjuvant Chemotherapy and Surgical Staging in Early-Stage Ovarian Carcinoma: European Organisation for Research and Treatment of Cancer-Adjuvant ChemoTherapy in Ovarian Neoplasm Trial

Baptist Trimbos, J.; Vergote, Ignace; Bolis, Giorgio; B. Vermorken, J.; Mangioni, C.; Madroñal, C.; Piergiuseppe Franchi, Massimo; Tateo, Saverio; Zanetta, Gerardo; Scarfone, G.; Giurgea, L.; Timmers, P.J.; Coens, C.; Pecorelli, S.

doi:10.1093/jnci/95.2.113

Public

Impact of Adjuvant Chemotherapy and Surgical Staging in Early-Stage Ovarian Carcinoma: European Organisation for Research and Treatment of Cancer-Adjuvant ChemoTherapy in Ovarian Neoplasm Trial

Published in JNCI Journal of the National Cancer Institute • Jan 14, 2003

Authors:

J. Baptist Trimbos

Ignace Vergote

Giorgio Bolis

Abstract

BACKGROUND: All randomized trials of adjuvant chemotherapy for early-stage ovarian cancer have lacked the statistical power to show a difference in the effect on survival between adjuvant chemotherapy and no adjuvant chemotherapy. They have also not taken into account the adequacy of surgical stagin...

Subject

Medicine

Hazard ratio

Chemotherapy

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