Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer

E. Ghayad, Sandra; A. Vendrell, Julie; Bièche, Ivan; Spyratos, Frédérique; Dumontet, Charles; Treilleux, Isabelle; Lidereau, Rosette; A. Cohen, Pascale

doi:10.1677/jme-08-0076

Public

Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer

Published in Journal of Molecular Endocrinology • Nov 3, 2008

Authors:

Sandra E. Ghayad

Julie A. Vendrell

Ivan Bièche

Abstract

Cross-resistance to molecules used in endocrine therapy is among the main challenges in the treatment of estrogen receptor-alpha (ERalpha) positive breast cancer. In this study, we used two different cell models of resistance to anti-estrogens: MVLN/CL6.7 cells and VP229/VP267 cells selected after e...

Subject

Breast cancer

Endocrine system

Identification (biology)

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