Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects

Dumonteil, Eric; Elena Bottazzi, María; Zhan, Bin; J. Heffernan, Michael; M. Jones, Kathryn; G. Valenzuela, Jesús; Kamhawi, Shaden; Ortega, Jaime; Ponce de León Rosales, Samuel; Y. Lee, Bruce; M. Bacon, Kristina; Fleischer, Bernhard; Slingsby, BT; Betancourt Cravioto, Miguel; Tapia‐Conyer, Roberto; J. Hotez, Peter

doi:10.1586/erv.12.85

Public

Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects

Published in Expert Review of Vaccines • Sep 1, 2012

Authors:

Eric Dumonteil

María Elena Bottazzi

Bin Zhan

Abstract

Chagas disease is a leading cause of heart disease affecting approximately 10 million people in Latin America and elsewhere worldwide. The two major drugs available for the treatment of Chagas disease have limited efficacy in Trypanosoma cruzi-infected adults with indeterminate (patients who have se...

Subject

Chagas disease

Medicine

Immunology

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