Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. II: Postnatal Evaluation

Sing Lau, Chak; R. Thibodeaux, J.; G. Hanson, Reginald; M. Rogers, John; E. Grey, Brian; E. Stanton, Mark; L. Butenhoff, John; A. Stevenson, L.

doi:10.1093/toxsci/kfg122

Public

Exposure to Perfluorooctane Sulfonate during Pregnancy in Rat and Mouse. II: Postnatal Evaluation

Published in Toxicological Sciences • May 28, 2003

Authors:

Chak Sing Lau

J. R. Thibodeaux

Reginald G. Hanson

Abstract

The postnatal effects of in utero exposure to perfluorooctane sulfonate (PFOS, C8F17SO3-) were evaluated in the rat and mouse. Pregnant Sprague-Dawley rats were given 1, 2, 3, 5, or 10 mg/kg PFOS daily by gavage from gestation day (GD) 2 to GD 21; pregnant CD-1 mice were treated with 1, 5, 10, 15, a...

Subject

Perfluorooctane

Offspring

Gestation

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