A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma

Léauté-Labrèze, Christine; H. Hoeger, Peter; Mazereeuw‐Hautier, J.; Guibaud, Laurent; Baselga, Eulàlia; Pošiūnas, Gintas; J. Phillips, Roderic; Cáceres, Héctor; Carlos López‐Gutiérrez, Juan; Ballona, Rosalía; Fallon Friedlander, Sheila; Powell, Julie; Perek, Danuta; Metz, B; Barbarot, S.; Maruani, A.; Szalai, Zsuzsanna; Krol, Alfons; Boccara, O.; Foelster‐Holst, R.; Isabel Bosch, Maria; Su, John; Bučková, Hana; Torrelo, Antonio; Cambazard, F.; Grantzow, R.; Wargon, Orli; Wyrzykowski, Dariusz; Roessler, Jochen; Bernabéu‐Wittel, José; Valencia, Adriana; Przewratil, Przemysław; A. Glick, Sharon; Pope, Elena; Birchall, Nicholas; Benjamin, Latanya; J. Mancini, Anthony; Vabres, P.; Souteyrand, P; J. Frieden, Ilona; I. Berul, Charles; R. Mehta, Cyrus; Prey, S.; Boralévi, F.; Morgan, Caroline; Héritier, Stéphane; Delarue, Alain; Voisard, J.-J.

doi:10.1056/nejmoa1404710

Public

A Randomized, Controlled Trial of Oral Propranolol in Infantile Hemangioma

Published in New England Journal of Medicine • Feb 18, 2015

Authors:

Christine Léauté-Labrèze

Peter H. Hoeger

J. Mazereeuw‐Hautier

Abstract

BACKGROUND: Oral propranolol has been used to treat complicated infantile hemangiomas, although data from randomized, controlled trials to inform its use are limited. METHODS: We performed a multicenter, randomized, double-blind, adaptive, phase 2-3 trial assessing the efficacy and safety of a pedia...

Subject

Propranolol

Infantile hemangioma

Randomized controlled trial

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