A hyperfused mitochondrial state achieved at G 1 –S regulates cyclin E buildup and entry into S phase

Mitochondria undergo fission–fusion events that render these organelles highly dynamic in cells. We report a relationship between mitochondrial form and cell cycle control at the G 1 –S boundary. Mitochondria convert from isolated, fragmented elements into a hyperfused, giant network at G 1 –S trans... View More