High-dose continuous infusion beta-lactam antibiotics for the treatment of resistant Pseudomonas aeruginosa infections in immunocompromised patients.

Moriyama, Brad; A Henning, Stacey; Childs, Richard; M Holland, Steven; L Anderson, Victoria; C Morris, John; H Wilson, Wyndham; L Drusano, George; J Walsh, Thomas

doi:10.1345/aph.1m717

Public

High-dose continuous infusion beta-lactam antibiotics for the treatment of resistant Pseudomonas aeruginosa infections in immunocompromised patients.

Published in The Annals of pharmacotherapy • May 1, 2010

NobleIDNI6P57W79R43S87

Authors:

Brad Moriyama

,

Stacey A Henning

,

Richard Childs

Abstract

OBJECTIVE: To report a case series of high-dose continuous infusion beta-lactam antibiotics for the treatment of resistant Pseudomonas aeruginosa infections. CASE SUMMARY: Continuous infusion ceftazidime or aztreonam was administered to achieve target drug concentrations at or above the minimum inhi...

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