Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex.

Y, Kimura; T, Takeshita; M, Kondo; N, Ishii; M, Nakamura; Snick J, Van; K, Sugamura

doi:10.1093/intimm/7.1.115

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Sharing of the IL-2 receptor gamma chain with the functional IL-9 receptor complex.

Shared by NobleBlocks on Jan 1, 1995 • 12:00 AM UTC

Authors:

Kimura Y

Takeshita T

Kondo M

Abstract

The third subunit, the so-called common gamma (gamma c) chain, of the IL-2 receptor is shared among the receptors for IL-2, IL-4, IL-7 and IL-15, and dysfunction of the gamma c chain is thought to cause X-linked severe combined immunodeficiency (XSCID) ascribed to impairment of early T cell developm...

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