Sharing of the IL-2 receptor γ chain with the functional IL-9 receptor complex

Kimura, Yutaka; Takeshita, Toshikazu; Kondo, Motonari; Ishii, Naoto; Nakamura, Masataka; Van Snick, Jacques; Sugamura, Kazuo

doi:10.1093/intimm/7.1.115

Public

Sharing of the IL-2 receptor γ chain with the functional IL-9 receptor complex

Published in International Immunology • Jan 1, 1995

Authors:

Yutaka Kimura

Toshikazu Takeshita

Motonari Kondo

Abstract

The third subunit, the so-called common gamma (gamma c) chain, of the IL-2 receptor is shared among the receptors for IL-2, IL-4, IL-7 and IL-15, and dysfunction of the gamma c chain is thought to cause X-linked severe combined immunodeficiency (XSCID) ascribed to impairment of early T cell developm...

Subject

Receptor

Chemistry

Interleukin-21 receptor

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