Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer.

A Forastiere, Arlene; Goepfert, Helmuth; Maor, Moshe; F Pajak, Thomas; Weber, Randal; Morrison, William; Glisson, Bonnie; Trotti, Andy; A Ridge, John; Chao, Clifford; Peters, Glen; Lee, Ding-Jen; Leaf, Andrea; Ensley, John; Cooper, Jay

doi:10.1056/nejmoa031317

Public

Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer.

Published in The New England journal of medicine • Nov 27, 2003

NobleIDark:/48914/w1/20260526/B2377635Record on NobleID

Authors:

Arlene A Forastiere

,

Helmuth Goepfert

,

Moshe Maor

Abstract

BACKGROUND: Induction chemotherapy with cisplatin plus fluorouracil followed by radiotherapy is the standard alternative to total laryngectomy for patients with locally advanced laryngeal cancer. The value of adding chemotherapy to radiotherapy and the optimal timing of chemotherapy are unknown. MET...

Discussions