Concurrent Chemotherapy and Radiotherapy for Organ Preservation in Advanced Laryngeal Cancer

A. Forastiere, Arlene; Goepfert, Helmuth; Maor, Moshe; F. Pajak, Thomas; S. Weber, Randal; H. Morrison, William; S. Glisson, Bonnie; Trotti, Andy; A. Ridge, John; Chao, C.; Peters, Glen; Lee, Ding-Jen; Leaf, Andrea; F. Ensley, John; S. Cooper, Jay

doi:10.1056/nejmoa031317

Public

Concurrent Chemotherapy and Radiotherapy for Organ Preservation in Advanced Laryngeal Cancer

Published in New England Journal of Medicine • Nov 26, 2003

Authors:

Arlene A. Forastiere

Helmuth Goepfert

Moshe Maor

Abstract

BACKGROUND: Induction chemotherapy with cisplatin plus fluorouracil followed by radiotherapy is the standard alternative to total laryngectomy for patients with locally advanced laryngeal cancer. The value of adding chemotherapy to radiotherapy and the optimal timing of chemotherapy are unknown. MET...

Subject

Radiation therapy

Medicine

Cisplatin

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