The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase

J. Passer, Brent; Nancy-Portebois, Vanessa; Amzallag, Nathalie; Prieur, Sylvie; Cans, Christophe; Roborel de Climens, Aude; Fiucci, Giusy; Bouvard, Véronique; Tuynder, Marcel; Susini, Laurent; Morchoisne, Stéphanie; Crible, Virginie; Lespagnol, Alexandra; Dausset, J; Oren, Moshe; Amson, Robert; Telerman, Adam

doi:10.1073/pnas.0530298100

Public

The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase

Published in Proceedings of the National Academy of Sciences • Feb 26, 2003

Authors:

Brent J. Passer

Vanessa Nancy-Portebois

Nathalie Amzallag

Abstract

The p53 tumor suppressor protein plays a crucial role in tumorigenesis by controlling cell-cycle progression and apoptosis. We have previously described a transcript designated tumor suppressor activated pathway-6 (TSAP6) that is up-regulated in the p53-inducible cell line, LTR6. Cloning of the muri...

Subject

Biology

Cell cycle

Carcinogenesis

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