<i>Mycobacterium tuberculosis</i>
                    lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b

V. S. Rajaram, Murugesan; Ni, Bin; D. Morris, Jessica; N. Brooks, Michelle; K. Carlson, Tracy; Bakthavachalu, Baskar; R. Schoenberg, Daniel; B. Torrelles, Jordi; S. Schlesinger, Larry

doi:10.1073/pnas.1112660108

Public

Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b

Shared by NobleBlocks on Oct 3, 2011 • 12:00 AM UTC

Authors:

Murugesan V. S. Rajaram

Bin Ni

Jessica D. Morris

Abstract

Contact of Mycobacterium tuberculosis ( M.tb ) with the immune system requires interactions between microbial surface molecules and host pattern recognition receptors. Major M.tb -exposed cell envelope molecules, such as lipomannan (LM), contain subtle structural variations that affect the nature of...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!