Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

J. McLaren, Paul; Coulonges, Cédric; Ripke, Stephan; van den Berg, Leonard; Buchbinder, Susan; Carrington, Mary; Cossarizza, Andrea; Dalmau, Judith; G. Deeks, Steven; Delaneau, Olivier; De Luca, Andrea; J. Goedert, James; W. Haas, David; T. Herbeck, Joshua; Kathiresan, Sekar; D. Kirk, Gregory; Lambotte, Olivier; Luo, Ma; Mallal, S.; van Manen, Daniëlle; Martínez‐Picado, Javier; Meyer, Laurence; M. Miró, José; I. Mullins, James; Obel, Niels; J. O’Brien, Stephen; Pereyra, Florencia; A. Plummer, Francis; Poli, Guido; Ying, Qi; Rucart, Pierre; S. Sandhu, Manj; R. Shea, Patrick; Schuitemaker, Hanneke; Théodorou, Ioannis; Vannberg, Fredrik; H. Veldink, Jan; D. Walker, Bruce; Weintrob, Amy; A. Winkler, Cheryl; M. Wolinsky, Steven; Telenti, Amalio; B. Goldstein, David; I. W. de Bakker, Paul; Zagury, Jean-François; Fellay, Jacques

doi:10.1371/journal.ppat.1003515

Public

Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls

Published in PLoS Pathogens • Jul 25, 2013

Authors:

Paul J. McLaren

Cédric Coulonges

Stephan Ripke

Abstract

Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have been interrogated using GWAS, although in gen...

Subject

Genome-wide association study

Imputation (statistics)

Genetic association

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