Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Gemcitabine Alone in Advanced Pancreatic Cancer

Heinemann, Volker; Quietzsch, D.; Gieseler, Frank; Gonnermann, Michael; Schönekäs, H; Rost, A.; Neuhaus, Horst; Haag, Caroline; Clemens, Michael; Heinrich, Bernard; Vehling‐Kaiser, Ursula; Fuchs, Martin; Fleckenstein, Doris; Gesierich, Wolfgang; Uthgenannt, D.; Einsele, Hermann; Holstege, Axel; Hinke, Axel; Schalhorn, Andreas; Wilkowski, Ralf

doi:10.1200/jco.2005.05.1490

Public

Randomized Phase III Trial of Gemcitabine Plus Cisplatin Compared With Gemcitabine Alone in Advanced Pancreatic Cancer

Published in Journal of Clinical Oncology • Aug 18, 2006

Authors:

Volker Heinemann

D. Quietzsch

Frank Gieseler

Abstract

PURPOSE: To compare the effectiveness and tolerability of gemcitabine plus cisplatin with single-agent gemcitabine as first-line chemotherapy for locally advanced or metastatic pancreatic cancer. PATIENTS AND METHODS: Patients with advanced adenocarcinoma of the pancreas were randomly assigned to re...

Subject

Gemcitabine

Medicine

Tolerability

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