Relationships between <i>Staphylococcus aureus</i> Genetic Background, Virulence Factors, <i>agr</i> Groups (Alleles), and Human Disease

Jarraud, Sophie; Mougel, Christophe; Thioulouse, Jean; Lina, Gérard; Meugnier, H.; Forey, Françoise; Nesme, Xavier; Étienne, Jérôme; Vandenesch, François

doi:10.1128/iai.70.2.631-641.2002

Public

Relationships between Staphylococcus aureus Genetic Background, Virulence Factors, agr Groups (Alleles), and Human Disease

Published in Infection and Immunity • Feb 1, 2002

Authors:

Sophie Jarraud

Christophe Mougel

Jean Thioulouse

Abstract

The expression of most Staphylococcus aureus virulence factors is controlled by the agr locus, which encodes a two-component signaling pathway whose activating ligand is an agr-encoded autoinducing peptide (AIP). A polymorphism in the amino acid sequence of the AIP and of its corresponding receptor ...

Subject

Biology

Virulence

Staphylococcus aureus

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