Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.

A, Cherubini; G, Hofmann; S, Pillozzi; L, Guasti; L, Guasti; O, Crociani; E, Cilia; Stefano P, Di; S, Degani; M, Balzi; M, Olivotto; E, Wanke; A, Becchetti; P, Defilippi; R, Wymore; A, Arcangeli

doi:10.1091/mbc.e04-10-0940

Public

Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.

Shared by NobleBlocks on Mar 30, 2005 • 12:00 AM UTC

Authors:

Cherubini A

Hofmann G

Pillozzi S

Abstract

Adhesive receptors of the integrin family are primarily involved in cell-extracellular matrix adhesion. Additionally, integrins trigger multiple signaling pathways that are involved in cell migration, proliferation, survival, and differentiation. We previously demonstrated that the activation of int...

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