Human <i>ether-a-go-go</i>-related Gene 1 Channels Are Physically Linked to β<sub>1</sub> Integrins and Modulate Adhesion-dependent Signaling

Cherubini, Alessia; Hofmann, Giovanna; Pillozzi, Serena; Guasti, Leonardo; Crociani, Olivia; Cilia, Emanuele; Di Stefano, Paola; Degani, Simona; Balzi, Manuela; Olivotto, Massimo; Wanke, Enzo; Becchetti, Andrea; Defilippi, Paola; S. Wymore, Randy; Arcangeli, Annarosa

doi:10.1091/mbc.e04-10-0940

Public

Human ether-a-go-go-related Gene 1 Channels Are Physically Linked to β1 Integrins and Modulate Adhesion-dependent Signaling

Published in Molecular Biology of the Cell • Mar 31, 2005

Authors:

Alessia Cherubini

Giovanna Hofmann

Serena Pillozzi

Abstract

Adhesive receptors of the integrin family are primarily involved in cell-extracellular matrix adhesion. Additionally, integrins trigger multiple signaling pathways that are involved in cell migration, proliferation, survival, and differentiation. We previously demonstrated that the activation of int...

Subject

Cell biology

Biology

Integrin

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