MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network

S. Bhalla, Upinder; T. Ram, Prahlad; Iyengar, Ravi

doi:10.1126/science.1068873

Public

MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network

Published in Science • Aug 9, 2002

Authors:

Upinder S. Bhalla

Prahlad T. Ram

Ravi Iyengar

Abstract

Intracellular signaling networks receive and process information to control cellular machines. The mitogen-activated protein kinase (MAPK) 1,2/protein kinase C (PKC) system is one such network that regulates many cellular machines, including the cell cycle machinery and autocrine/paracrine factor sy...

Subject

MAPK/ERK pathway

Cell biology

Autocrine signalling

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