Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

J. Aryee, Martin; E. Jaffe, Andrew; Corrada Bravo, Héctor; Ladd‐Acosta, Christine; P. Feinberg, Andrew; D. Hansen, Kasper; A. Irizarry, Rafael

doi:10.1093/bioinformatics/btu049

Public

Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays

Published in Bioinformatics • Jan 28, 2014

Authors:

Martin J. Aryee

Andrew E. Jaffe

Héctor Corrada Bravo

Abstract

MOTIVATION: The recently released Infinium HumanMethylation450 array (the '450k' array) provides a high-throughput assay to quantify DNA methylation (DNAm) at ∼450 000 loci across a range of genomic features. Although less comprehensive than high-throughput sequencing-based techniques, this product ...

Subject

Bioconductor

dNaM

Computer science

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