Chronic Exposure to Beta-Blockers Attenuates Inflammation and Mucin Content in a Murine Asthma Model

Nguyễn, Long; Omoluabi, Ozozoma; Parra, Sergio; M. Frieske, Joanna; Clement, Cecilia; Ammar-Aouchiche, Zoulikha; B. Ho, Samuel; Ehré, Camille; Kesımer, Mehmet; J. Knoll, Brian; J. Tuvim, Michael; F. Dickey, Burton; A. Bond, Richard

doi:10.1165/rcmb.2007-0279rc

Public

Chronic Exposure to Beta-Blockers Attenuates Inflammation and Mucin Content in a Murine Asthma Model

Published in American Journal of Respiratory Cell and Molecular Biology • Dec 20, 2007

Authors:

Long Nguyễn

Ozozoma Omoluabi

Sergio Parra

Abstract

Single-dose administration of beta-adrenoceptor agonists produces bronchodilation and inhibits airway hyperresponsiveness (AHR), and is the standard treatment for the acute relief of asthma. However, chronic repetitive administration of beta-adrenoceptor agonists may increase AHR, airway inflammatio...

Subject

Inflammation

Asthma

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