Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

M. Parfitt, A.; H. E. Mathews, Catharina; R. Villanueva, A.; Kleerekoper, Michael; Frame, Boy; Srinivasa Rao, D.

doi:10.1172/jci111096

Public

Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

Published in Journal of Clinical Investigation • Oct 1, 1983

Authors:

A. M. Parfitt

Catharina H. E. Mathews

A. R. Villanueva

Abstract

We devised a new method for examining the structural changes that occur in trabecular bone in aging and in osteoporosis. With simultaneous measurement of total perimeter and bone area in thin sections, indirect indices of mean trabecular plate thickness (MTPT) and mean trabecular plate density (MTPD...

Subject

Osteoporosis

Reduction (mathematics)

Bone density

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