Detection of primary cytotoxic T lymphocytes specific for the envelope glycoprotein of HIV‐1 by deletion of the env amino‐terminal signal sequence

B. McChesney, Michael; Tanneau, Françoise; Régnault, Armelle; Sansonetti, Philippe; Montagnier, Luc; Paule Kiény, Marie; Rivière, Yves

doi:10.1002/eji.1830200131

Public

Detection of primary cytotoxic T lymphocytes specific for the envelope glycoprotein of HIV‐1 by deletion of the env amino‐terminal signal sequence

Published in European Journal of Immunology • Jan 1, 1990

Authors:

Michael B. McChesney

Françoise Tanneau

Armelle Régnault

Abstract

A heterogenous population of envelope glycoprotein-specific cytotoxic effector cells are found in the peripheral blood of individuals infected with HIV-1, and in many cases env-specific lysis is not restricted by MHC molecules and is not blocked by antibody to CD3 (Rivière, Y. et al., J. Virol. 1989...

Subject

CTL*

Biology

Cytotoxic T cell

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