Short‐chain fatty acid sensing in rat duodenum

Akiba, Yasutada; Inoue, Takuya; Kaji, Izumi; Higashiyama, Masaaki; Narimatsu, Kazuyuki; Iwamoto, Ken‐ichi; Watanabe, Masahiko; H. Guth, Paul; Engel, Eli; Kuwahara, Atsukazu; D. Kaunitz, Jonathan

doi:10.1113/jphysiol.2014.280792

Public

Short‐chain fatty acid sensing in rat duodenum

Published in The Journal of Physiology • Nov 29, 2014

Authors:

Yasutada Akiba

Takuya Inoue

Izumi Kaji

Abstract

KEY POINTS: Luminal lipid in the duodenum modulates gastroduodenal functions via the release of gut hormones and mediators such as cholecystokinin and 5-HT. The effects of luminal short-chain fatty acids (SCFAs) in the foregut are unknown. Free fatty acid receptors (FFARs) for long-chain fatty acids...

Subject

Enteroendocrine cell

Endocrinology

G protein-coupled bile acid receptor

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