Mouse CD8+ CD122+ T Cells with Intermediate TCR Increasing with Age Provide a Source of Early IFN-γ Production

Takayama, Eiji; Seki, Shuhji; Ohkawa, Takashi; Ami, Katsunori; Habu, Yoshiko; Yamaguchi, Takanori; Tadakuma, Takushi; Hiraide, Hoshio

doi:10.4049/jimmunol.164.11.5652

Public

Mouse CD8+ CD122+ T Cells with Intermediate TCR Increasing with Age Provide a Source of Early IFN-γ Production

Published in The Journal of Immunology • Jun 1, 2000

Authors:

Eiji Takayama

Shuhji Seki

Takashi Ohkawa

Abstract

Although CD8+ IL-2Rbeta (CD122)+ T cells with intermediate TCR reportedly develop extrathymically, their functions still remain largely unknown. In the present study, we characterized the function of CD8+ CD122+ T cells with intermediate TCR of C57BL/6 mice. The proportion of CD8+ CD122+ T cells in ...

Subject

CD8

Cytotoxic T cell

Interleukin 21

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