A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis.

Background Inhaled hypertonic saline acutely increases mucociliary clearance and, in short-term trials, improves lung function in people with cystic fibrosis. We tested the safety and efficacy of inhaled hypertonic saline in a long-term trial.Methods In this double-blind, parallel-group trial, 164 p... View More