Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group

Wang, Xuexia; Liu, Wei; Sun, Can-Lan; H. Armenian, Saro; Håkonarson, Håkon; Hageman, Lindsey; Ding, Yan; Landier, Wendy; G. Blanco, Javier; Chen, Lu; Quiñones, Adolfo; C. Ferguson, Daniel; Winick, Naomi; P. Ginsberg, Jill; G. Keller, Frank; P. Neglia, Joseph; Desai, Sunil; A. Sklar, Charles; M. Castellino, Sharon; Cherrick, Irene; E. Dreyer, ZoAnn; M. Hudson, Melissa; L. Robison, Leslie; Yasui, Yutaka; V. Relling, Mary; Bhatia, Ravi

doi:10.1200/jco.2013.50.3557

Public

Hyaluronan Synthase 3 Variant and Anthracycline-Related Cardiomyopathy: A Report From the Children's Oncology Group

Published in Journal of Clinical Oncology • Jan 28, 2014

Authors:

Xuexia Wang

Wei Liu

Can-Lan Sun

Abstract

PURPOSE: The strong dose-dependent association between anthracyclines and cardiomyopathy is further exacerbated by the co-occurrence of cardiovascular risk factors (diabetes and hypertension). The high morbidity associated with cardiomyopathy necessitates an understanding of the underlying pathogene...

Subject

Cardiomyopathy

Anthracycline

Medicine

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