Enhanced T-Cell Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 1 Vaccine Regimen Consisting of Consecutive Priming with DNA and Boosting with Recombinant Fowlpox Virus

J. Kent, Stephen; Zhao, Anne; J. Best, Susan; D. Chandler, Jenalle; B. Boyle, David; A. Ramshaw, Ian

doi:10.1128/jvi.72.12.10180-10188.1998

Public

Enhanced T-Cell Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 1 Vaccine Regimen Consisting of Consecutive Priming with DNA and Boosting with Recombinant Fowlpox Virus

Published in Journal of Virology • Dec 1, 1998

Authors:

Stephen J. Kent

Anne Zhao

Susan J. Best

Abstract

The induction of human immunodeficiency virus (HIV)-specific T-cell responses is widely seen as critical to the development of effective immunity to HIV type 1 (HIV-1). Plasmid DNA and recombinant fowlpox virus (rFPV) vaccines are among the most promising safe HIV-1 vaccine candidates. However, the ...

Subject

Fowlpox virus

Virology

Biology

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