Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

J. Perrin, Richard; Craig‐Schapiro, Rebecca; P. Malone, James; R. Shah, Aarti; Erdmann-Gilmore, Petra; Davis, Alan; M. Roe, Catherine; R. Peskind, Elaine; Li, Ge; Galasko, Douglas; M. Clark, Christopher; F. Quinn, Joseph; Kaye, Jeffrey; C. Morris, John; M. Holtzman, David; Reid Townsend, R.; M. Fagan, Anne

doi:10.1371/journal.pone.0016032

Public

Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease

Published in PLoS ONE • Jan 12, 2011

Authors:

Richard J. Perrin

Rebecca Craig‐Schapiro

James P. Malone

Abstract

BACKGROUND: Ideally, disease modifying therapies for Alzheimer disease (AD) will be applied during the 'preclinical' stage (pathology present with cognition intact) before severe neuronal damage occurs, or upon recognizing very mild cognitive impairment. Developing and judiciously administering such...

Subject

Biomarker

Chromogranin A

Cerebrospinal fluid

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!