Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

M. Grant, Robert; R. Lama, Javier; L. Anderson, Peter; McMahan, Vanessa; Liu, Albert; Vargas, Lorena; Goicochea, Pedro; Casapía, Martín; V. Guanira, Juan; Esther Ramirez-Cardich, Maria; Montoya-Herrera, Orlando; Fernández, Telmo; G. Veloso, Valdiléa; Buchbinder, Susan; Chariyalertsak, Suwat; Schechter, Mauro; Bekker, Linda‐Gail; H. Mayer, Kenneth; G. Kallás, Esper; Rivet Amico, K.; Mulligan, Kathleen; R. Bushman, Lane; Hance, Robert; Ganoza, Carmela; Defechereux, Patricia; S. Postle, Brian; Wang, Furong; Jeff McConnell, J.; Zheng, Jia‐Hua; Lee, Jeanny; F. Rooney, James; S. Jaffe, Howard; I. Martínez, Ana; Burns, David; V. Glidden, David

doi:10.1056/nejmoa1011205

Public

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

Published in New England Journal of Medicine • Nov 23, 2010

Authors:

Robert M. Grant

Javier R. Lama

Peter L. Anderson

Abstract

BACKGROUND: Antiretroviral chemoprophylaxis before exposure is a promising approach for the prevention of human immunodeficiency virus (HIV) acquisition. METHODS: We randomly assigned 2499 HIV-seronegative men or transgender women who have sex with men to receive a combination of two oral antiretrov...

Subject

Medicine

Emtricitabine

Chemoprophylaxis

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