Rheumatoid Factor as a Potentiator of Anti–Citrullinated Protein Antibody–Mediated Inflammation in Rheumatoid Arthritis

Sokolove, Jeremy; S. Johnson, Dannette; J. Lahey, Lauren; A. Wagner, Catriona; Cheng, Danye; M. Thiele, Geoffrey; Michaud, Kaleb; Sayles, Harlan; Reimold, Andreas; Caplan, Liron; W. Cannon, Grant; S. Kerr, Gail; R. Mikuls, Ted; H. Robinson, William

doi:10.1002/art.38307

Public

Rheumatoid Factor as a Potentiator of Anti–Citrullinated Protein Antibody–Mediated Inflammation in Rheumatoid Arthritis

Published in Arthritis & Rheumatology • Jan 27, 2014

Authors:

Jeremy Sokolove

Dannette S. Johnson

Lauren J. Lahey

Abstract

OBJECTIVE: The co-occurrence of rheumatoid factor (RF) and anti-citrullinated protein antibody (ACPA) positivity in rheumatoid arthritis (RA) is well described. However, the mechanisms underlying the potential interaction between these 2 distinct autoantibodies have not been well defined. The aim of...

Subject

Rheumatoid arthritis

Potentiator

Rheumatoid factor

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