Characterizing the cancer genome in lung adenocarcinoma

A. Weir, Barbara; Sue‐Ann Woo, Michele; Getz, Gad; Perner, Sven; Ding, Li; Beroukhim, Rameen; M. Lin, William; A. Province, Michael; T. Kraja, Aldi; A. Johnson, Laura; Shah, Kinjal; Sato, Mitsuo; K. Thomas, Roman; A. Barletta, Justine; B. Borecki, Ingrid; Broderick, Stephen; C. Chang, Andrew; Y. Chiang, Derek; R. Chirieac, Lucian; Cho, Jeonghee; Fujii, Yoshitaka; F. Gazdar, Adi; J. Giordano, Thomas; Greulich, Heidi; Hanna, Megan; E. Johnson, Bruce; G. Kris, Mark; Lash, Alex; Lin, Ling; I. Lindeman, Neal; R. Mardis, Elaine; D. McPherson, John; D. Minna, John; Morgan, Margaret; Nadel, Mark; B. Orringer, Mark; R. Osborne, John; Ozenberger, Brad; H. Ramos, Alex; Robinson, James; A. Roth, Jack; W. Rusch, Valerie; Sasaki, Hidefumi; A. Shepherd, Frances; Sougnez, Carrie; R. Spitz, Margaret; Tsao, Ming‐Sound; Twomey, David; G.W. Verhaak, Roel; M. Weinstock, George; A. Wheeler, David; Winckler, Wendy; Yoshizawa, Akihiko; Yu, Soyoung; F. Zakowski, Maureen; Zhang, Qunyuan; G. Beer, David; I. Wistuba, Ignacio; A. Watson, Mark; A. Garraway, Levi; Ladanyi, Marc; D. Travis, William; Pao, William; A. Rubin, Mark; Gabriel, Stacey; A. Gibbs, Richard; Varmus, Harold; K. Wilson, Richard; S. Lander, Eric; Meyerson, Matthew

doi:10.1038/nature06358

Public

Characterizing the cancer genome in lung adenocarcinoma

Published in Nature • Nov 4, 2007

Authors:

Barbara A. Weir

Michele Sue‐Ann Woo

Gad Getz

Abstract

A wide-ranging overview of genetic alterations in lung adenocarcinomas, published in this issue, takes a new approach to genome analysis. The analysis of 371 tumours revealed 31 recurrent focal events, only six of which were known previously in lung carcinomas. A new candidate oncogene, TITF1, was f...

Subject

Biology

Adenocarcinoma

Genome

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