Phase III, Open-Label, Randomized Study Comparing Concurrent Gemcitabine Plus Cisplatin and Radiation Followed by Adjuvant Gemcitabine and Cisplatin Versus Concurrent Cisplatin and Radiation in Patients With Stage IIB to IVA Carcinoma of the Cervix

Dueñas‐González, Alfonso; José Zarbá, Juan; D. Patel, Firuza; Carlos Alcedo, Juan; Beslija, S.; Casanova, Luís; Pattaranutaporn, Pittayapoom; Hameed, Shahid; M. Blair, Julie; Barraclough, Helen; Orlando, Mauro

doi:10.1200/jco.2009.25.9663

Public

Phase III, Open-Label, Randomized Study Comparing Concurrent Gemcitabine Plus Cisplatin and Radiation Followed by Adjuvant Gemcitabine and Cisplatin Versus Concurrent Cisplatin and Radiation in Patients With Stage IIB to IVA Carcinoma of the Cervix

Published in Journal of Clinical Oncology • Mar 28, 2011

Authors:

Alfonso Dueñas‐González

Juan José Zarbá

Firuza D. Patel

Abstract

PURPOSE: To determine whether addition of gemcitabine to concurrent cisplatin chemoradiotherapy and as adjuvant chemotherapy with cisplatin improves progression-free survival (PFS) at 3 years compared with current standard of care in locally advanced cervical cancer. PATIENTS AND METHODS: Eligible c...

Subject

Gemcitabine

Medicine

Cisplatin

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